NPR does Arsenic, Apples, and Rice

On my way home from Texarkana I heard a short story on NPR regarding the FDA developing a threshold for arsenic in Apple Juice.

Here's some news for parents of the sippy-cup crowd: The Food and Drug Administration has proposed a 10 parts-per-billion threshold for levels of inorganic arsenic in apple juice. This is the same level set by the EPA for arsenic in drinking water. Right now, there is no FDA standard for apple juice.

Not this again, I thought.  I wrote about this...a lot, in a number of posts starting with this one for Apple Juice;  Apples, Arsenic, and Risk - Part 1: One in 500 and this one for rice; Arsenic in Rice: Part 1 - We Meet Again.

I am no fan of Dr. Oz and Consumer Reports for taking on this topic.  The science does not support their conclusion of risk.  All you gotta do is read my 30 or so posts to see that.  Or you can trust me, I write a blog.

My argument as to why it is bad science is based on this concept of toxicology:

If the dose is low enough even a highly toxic substance will cease to cause a harmful effect. The toxic potency of a chemical is thus ultimately defined by the dose (the amount) of the chemical that will produce a specific response in a specific biological system.

That's what they tell us on the Yale web page that defines the term "dose." That's the same thing Dr. Honeycutt with the Texas Commission on Environmental Quality (TCEQ) states:

The phrase, “the dose makes the poison,” is attributed to the ‘father’ of toxicology, Paracelsus (1493-1541). What he described was the dose-response concept and it is one of the fundamental ideas in assessing risk, in that, typically at higher doses the severity of an adverse effect increases.

I describe dose as a threshold and have shown it in my past posts as a line in the sand.

So the FDA is going to make "10 ppb" the new safe threshold.  Yay!!  Now apple juice that is less than that will be "safe."  Glad we got that settled.  So what's my issue?  Well for one thing - for the only thing in my opinion - that 10 ppb a'int based on science!

"We are pleased to see the Food and Drug Administration taking this action," says Urvashi Rangan, director of consumer safety and sustainability at Consumer Reports. "Proposing a 10 ppb guidance for apple juice — the same level set for water — is a reasonable first step in protecting consumers from unnecessary exposure to arsenic."

No, no it is not "reasonable."  Reasonable is based on the science of toxicology and risk. That 10 ppb in water, the MCL, is based on the safe dose of arsenic in drinking water.  That safe dose is derived from looking at the risk of 10 ppb in one liter of water.  It is based on a lifetime consumption of 2 liters of water over a 70 year lifetime.

Lifetime HA is for a 70 kg adult. The daily drinking water consumption for the 10 kg child and 70 kg adult are assumed to be 1 L/day and 2 L/day, respectively. The Lifetime HA for the drinking water contaminant is calculated from its associated Drinking Water Equivalent Level (DWEL), obtained from its RfD, and incorporates a drinking water Relative Source Contribution (RSC) factor of contaminant-specific data or a default of 20% of total exposure from all sources. (EPA)

Setting the dose - or safe threshold - for arsenic in apple juice to 10 ppb means that Consumer Reports thinks it reasonable that 2 liters of apple juice will be consumed for 70 years.  That's what I take issue with.  The safe level is not based on science and Consumer Reports should be basing their being "pleased" on science. Period

So what happened here?  FDA caved in to public pressure.  You can fight for science, but you are going to lose when science based organizations like Consumer Reports are incapable of grasping the concept.

Basically FDA found that almost all Apple Juice contains less than 10 ppb of arsenic anyway, so let's give the baby their bottle and make the safe threshold 10 ppb.  Done!.  But...but...that's not based on science.  Put a cork in it Bowman, this battle is over.  Science lost and the public is made stupider for thinking 10 ppb is "safe," but in the end, everyone wins.  Well, except science...

On the positive side, NPR just moved up a couple of notches in my book.  Well at least Allison Aubry did.

Here is how she summed it all up.

I would say, overall, Audie, for apple juice, I think the message is stand down. I mean, I can tell you as a mom of three children, from teen to toddler, I used to worry about all of these things. But if you look at the science here, if arsenic is limited down to 10 parts per billion, I think that this is something that we can mark off our worry list.

Thank you Allison Aubry...thank you!  That's exactly what I spent tens of thousands of words trying to show.  That sounds so good to hear her say that:

But if you look at the science here, if arsenic is limited down to 10 parts per billion, I think that this is something that we can mark off our worry list.

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